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A Direct Amine‐Palladium Acetate Cocatalyzed Saegusa Oxidation Reaction of Unmodified Aldehydes to α,β‐Unsaturated Aldehydes
Author(s) -
Zhu Jin,
Liu Jie,
Ma Ruoqun,
Xie Hexin,
Li Jian,
Jiang Hualiang,
Wang Wei
Publication year - 2009
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200900011
Subject(s) - chemistry , enol , palladium , silylation , amine gas treating , organic chemistry , aldehyde , catalysis , photochemistry
A direct preparation of synthetically useful α,β‐unsaturated aldehydes from readily available aldehydes has been developed. The process is effectively cocatalyzed by an amine‐palladium acetate to give rise to α,β‐unsaturated aldehydes in moderate to good yields (41–62%). The reaction features the use of unmodified aldehydes rather than enol silyl ethers, which are used in a typical Saegusa oxidation reaction.