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Ligand‐Free Iron/Copper Cocatalyzed Alkynylation Coupling Reactions
Author(s) -
Mao Jincheng,
Xie Guanlei,
Wu Minyan,
Guo Jun,
Ji Shunjun
Publication year - 2008
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200800517
Subject(s) - alkynylation , chemistry , ligand (biochemistry) , halide , aryl , coupling (piping) , coupling reaction , environmentally friendly , copper , combinatorial chemistry , catalysis , organic chemistry , metallurgy , ecology , biochemistry , alkyl , receptor , biology , materials science
Ligand‐free iron/copper cocatalyzed cross‐coupling reactions of aryl halides with terminal alkynes were carried out to provide the corresponding coupling products in good yields (up to 99%). Noteworthy is that this low‐cost, effective and environmentally friendly protocol was the first to be employed in alkynylation couplings.