Indium(III) Chloride‐Catalyzed Propargylation/Amination/Cycloisomerization Tandem Reaction: One‐Pot Synthesis of Highly Substituted Pyrroles from Propargylic Alcohols, 1,3‐Dicarbonyl Compounds and Primary Amines | Zendy

Liu Xiaotao | Zendy; Huang Lei | Zendy; Zheng Feijian | Zendy; Zhan Zhuangping | Zendy

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Indium(III) Chloride‐Catalyzed Propargylation/Amination/Cycloisomerization Tandem Reaction: One‐Pot Synthesis of Highly Substituted Pyrroles from Propargylic Alcohols, 1,3‐Dicarbonyl Compounds and Primary Amines

Author(s) -

Liu Xiaotao,

Huang Lei,

Zheng Feijian,

Zhan Zhuangping

Publication year - 2008

Publication title -

advanced synthesis and catalysis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.541

H-Index - 155

eISSN - 1615-4169

pISSN - 1615-4150

DOI - 10.1002/adsc.200800473

Subject(s) - cycloisomerization , chemistry , catalysis , amination , indium , tandem , primary (astronomy) , organic chemistry , chloride , one pot synthesis , combinatorial chemistry , materials science , physics , astronomy , composite material

A convenient one‐pot propargylation/amination/cycloisomerization tandem process has been developed for the synthesis of highly substituted pyrroles derivatives from propargylic alcohols, 1,3‐dicarbonyl compounds and primary amines using indium(III) chloride as a multifunctional catalyst. This method provides a flexible and rapid route to substituted pyrroles.

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