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Efficient Synthesis of γ,δ‐Alkynyl‐β‐amino Acid Derivatives by a New Copper‐Catalyzed Amine‐Alkyne‐Alkyne Addition Reaction
Author(s) -
Zhou Lei,
Jiang Huanfeng,
Li ChaoJun
Publication year - 2008
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200800447
Subject(s) - alkyne , chemistry , amine gas treating , catalysis , copper , combinatorial chemistry , organic chemistry
A simple and efficient method for the synthesis of γ,δ‐alkynyl‐β‐amino acid derivatives by a new copper‐catalyzed amines‐alkynes‐alkynes addition was developed. Various γ,δ‐alkynyl‐β‐amino acid derivatives were obtained in moderate to good yields in one step.