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Highly Efficient Brønsted Acid‐Catalyzed Cycloisomerizations of Alkynes Bearing Bis(acetoxy) Groups to Indenyl Ketones
Author(s) -
Liu Yuanhong,
Zhou Shaolin,
Li Guijie,
Yan Bin,
Guo Shenghai,
Zhou Yebing,
Zhang Hao,
Wang Peng George
Publication year - 2008
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200800037
Subject(s) - cycloisomerization , chemistry , catalysis , brønsted–lowry acid–base theory , reaction conditions , organic chemistry , medicinal chemistry , combinatorial chemistry
A Brønsted acid‐catalyzed cycloisomerization of functionalized alkynes is described, which is assumed to be initiated through the formation of a benzylic cation intermediate. The reaction offers a highly efficient and straightforward route to indenyl ketones with a wide range of substituents under mild conditions.