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Iridium‐Catalyzed Asymmetric Hydrogenation of Vinyl Ethers
Author(s) -
Zhu Ye,
Burgess Kevin
Publication year - 2008
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200700546
Subject(s) - chemistry , catalysis , iridium , carbene , organic chemistry , enol , alcohol , oxazoline , vinyl ether , copolymer , polymer
A carbene‐oxazoline catalyst 1 proved to be an effective catalyst for reduction of an enol ether that the literature suggested could not be hydrogenated effectively by P,N ‐Ir catalysts. Thus, a series of ester and alcohol substrates were hydrogenated using catalyst 1 . Good to excellent enantioselectivities and high conversions were obtained.