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A New Hybrid Phosphine Ligand for Palladium‐Catalyzed Amination of Aryl Halides
Author(s) -
Suzuki Ken,
Hori Yoji,
Kobayashi Tohru
Publication year - 2008
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200700543
Subject(s) - phosphine , chemistry , aryl , halide , palladium , amination , alkyl , ligand (biochemistry) , catalysis , combinatorial chemistry , organic chemistry , aryl halide , medicinal chemistry , biochemistry , receptor
A new hybrid phosphine was designed. The phosphine combines two common structural characteristics found among the effective phosphine ligands reported recently, namely, three tert ‐alkyl substituents binding to the phosphorus and an aryl group at an appropriate position. A hybrid phospine/palladium system is versatile and effective for the coupling reaction of various aryl halides with primary and secondary amines including carbazole.