Premium
Iron‐Catalyzed CN Cross‐Coupling of Sulfoximines with Aryl Iodides
Author(s) -
Correa Arkaitz,
Bolm Carsten
Publication year - 2008
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200700508
Subject(s) - chemistry , catalysis , aryl , environmentally friendly , combinatorial chemistry , palladium , copper , reaction conditions , organic chemistry , ecology , alkyl , biology
An inexpensive and experimentally simple, iron‐catalyzed N ‐arylation reaction of NH ‐sulfoximines with aryl iodides is reported. This complementary method to the known palladium‐ and copper‐catalyzed ones features the use of a combination of environmentally friendly FeCl 3 and N,N′ ‐dimethylethylenediamine (DMEDA) as catalytic system and allows the efficient preparation of various N ‐arylsulfoximines in high yields.