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Palladium(II)‐Catalyzed One‐Pot Enantioselective Synthesis of Arylglycine Derivatives from Ethyl Glyoxylate, p ‐Toluenesulfonyl Isocyanate and Arylboronic Acids
Author(s) -
Dai Huixiong,
Yang Miao,
Lu Xiyan
Publication year - 2008
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200700362
Subject(s) - chemistry , enantioselective synthesis , isocyanate , palladium , glyoxylate cycle , catalysis , organic chemistry , combinatorial chemistry , enzyme , polyurethane
A palladium(II)‐catalyzed, one‐pot enantioselective synthesis of arylglycine derivatives from ethyl glyoxylate, p ‐toluenesulfonyl isocyanate and arylboronic acids giving moderate to good yields and enantioselectivity has been developed. This reaction provides a convenient and efficient method for the synthesis of arylglycines.