Premium Auto‐Tandem Catalysis: Synthesis of Substituted 11 H ‐Indolo[3,2‐ c ]quinolines via Palladium‐Catalyzed Intermolecular CN and Intramolecular CC Bond FormationPremium
Author(s)
Meyers Caroline,
Rombouts Geert,
Loones Kristof T. J.,
Coelho Alberto,
Maes Bert U. W.
Publication year2008
Publication title
advanced synthesis and catalysis
Resource typeJournals
PublisherWILEY‐VCH Verlag
Abstract D ‐Ring substituted 11 H ‐indolo[3,2‐ c ]quinolines ( 4 ) have been prepared via auto‐tandem consecutive intermolecular Buchwald‐Hartwig reaction and intramolecular palladium‐catalyzed arylation on 4‐chloroquinoline ( 1 ) with N ‐unsubstituted 2‐chloroanilines ( 2 ). The reported 11 H ‐indolo[3,2‐ c ]quinolines ( 4 ) represent the first examples in which tandem catalysis has been used to construct N ‐unsubstituted carbolines.
Subject(s)cascade reaction , catalysis , chemistry , combinatorial chemistry , composite material , intermolecular force , intramolecular force , materials science , medicinal chemistry , molecule , organic chemistry , palladium , ring (chemistry) , stereochemistry , tandem
Language(s)English
SCImago Journal Rank1.541
H-Index155
eISSN1615-4169
pISSN1615-4150
DOI10.1002/adsc.200700328
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