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Chiral Bicyclic Guanidine as a Versatile Brønsted Base Catalyst for the Enantioselective Michael Reactions of Dithiomalonates and β‐Keto Thioesters
Author(s) -
Ye Weiping,
Jiang Zhiyong,
Zhao Yujun,
Goh Serena Li Min,
Leow Dasheng,
Soh YingTeck,
Tan ChoonHong
Publication year - 2007
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200700326
Subject(s) - enantioselective synthesis , chemistry , guanidine , bicyclic molecule , michael reaction , catalysis , brønsted–lowry acid–base theory , organocatalysis , base (topology) , organic chemistry , combinatorial chemistry , mathematical analysis , mathematics
A chiral bicyclic guanidine was developed as a versatile Brønsted base catalyst for the enantioselective Michael reactions of dithiomalonates and β‐keto thioesters using a range of acceptors including maleimides, cyclic enones, furanone and acyclic 1,4‐dicarbonylbutenes.