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A Novel (2,2‐Diarylvinyl)phosphine/Palladium Catalyst for Effective Aromatic Amination
Author(s) -
Suzuki Ken,
Hori Yoji,
Nishikawa Takenobu,
Kobayashi Tohru
Publication year - 2007
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200700220
Subject(s) - chemistry , palladium , amination , catalysis , phosphine , aryl , moiety , ligand (biochemistry) , combinatorial chemistry , organic chemistry , coupling reaction , biochemistry , alkyl , receptor
A new series of diarylvinylphosphine ligands was designed and synthesized. A catalyst system, consisting of the ligands and palladium species, effectively catalyzed the coupling reaction of aryl bromides and chlorides with amines to afford the corresponding products in good to excellent yields. The efficiency is likely derived from an interaction between the palladium center and the cis ‐aryl moiety on the diarylvinylphosphine ligand stabilizing a catalytic intermediate during the coupling reaction.