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Polymer‐Bound Pyridine‐Bis(oxazoline). Preparation through Click Chemistry and Evaluation in Asymmetric Catalysis
Author(s) -
Tilliet Mélanie,
Lundgren Stina,
Moberg Christina,
Levacher Vincent
Publication year - 2007
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200700112
Subject(s) - chemistry , click chemistry , catalysis , cycloaddition , oxazoline , pyridine , benzaldehyde , polymer chemistry , alkyne , cyclohexene , azide , polystyrene , organic chemistry , combinatorial chemistry , polymer
A pyridine‐bis(oxazoline) ligand was efficiently immobilized by copper(I)‐catalyzed azide‐alkyne cycloaddition onto a polystyrene resin. The so obtained click‐pybox resin 1a was associated with various metal salts (YbCl 3 , LuCl 3 , CuOTf) and the resulting resin‐bound catalysts were explored in ring‐opening of cyclohexene oxide, silylcyanation of benzaldehyde and alkynylation of imines. These new polymer‐supported catalysts exhibit good to excellent performances in terms of catalytic activity, enantioselectivity and recyclability.