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Gold(I)‐ and Brønsted Acid‐Catalyzed Ring‐Opening of Unactivated Vinylcyclopropanes with Sulfonamides
Author(s) -
Shi WenJian,
Liu Yanyun,
Butti Pietro,
Togni Antonio
Publication year - 2007
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200700006
Subject(s) - chemistry , ring (chemistry) , brønsted–lowry acid–base theory , catalysis , amine gas treating , medicinal chemistry , combinatorial chemistry , organic chemistry
Abstract The gold(I)‐ or Brønsted acid‐catalyzed reaction of unactivated vinylcyclopropanes (VCPs) with sulfonamides affords useful homoallylic amine derivatives. This ring‐opening reaction occurs in a highly selective manner affording in the case of α‐phenyl‐substituted VCPs products with the E ‐configuration exclusively.