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Laccase‐Mediated Oxidation of Totarol
Author(s) -
Ncanana Sandile,
Baratto Lara,
Roncaglia Lucia,
Riva Sergio,
Burton Stephanie G
Publication year - 2007
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200700005
Subject(s) - chemistry , laccase , solvent , phenol , organic chemistry , carbon fibers , oxidase test , enzyme , materials science , composite number , composite material
In this study, novel dimers of the biologically active phenolic compound totarol were synthesized using the phenol oxidase enzyme laccase, obtained from Trametes pusbescens , in organic solvent medium. Two dimeric products, linked either by carbon‐carbon or by carbon‐oxygen bonds, were isolated and characterized. The effect of changes in various parameters such as solvent, temperature, pH and buffer concentration on the conversion of totarol by laccase was investigated. The nature of the organic solvent, in particular, was found to affect the nature and the ratio of the products obtained.