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Efficient Enantioselective Hydrosilylation of Aryl Ketones Catalyzed by a Chiral BINAP‐Copper( I ) Catalyst‐Phenyl(methyl)silane System
Author(s) -
Issenhuth Jean Thomas,
Dagorne Samuel,
BelleminLaponnaz Stéphane
Publication year - 2006
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200606152
Subject(s) - hydrosilylation , chemistry , binap , silane , aryl , catalysis , enantioselective synthesis , hydride , organic chemistry , copper , alkyl , stoichiometry , medicinal chemistry , polymer chemistry , metal
The Cu(I)‐chiral diphosphine (BINAP) system was found to efficiently catalyze the hydrosilylation of aryl alkyl ketones with excellent enantioselectivities by using phenyl(methyl)silane as stoichiometric hydride source.

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