Premium
Zinc‐Catalyzed Enantioselective Hydrosilylation of Imines
Author(s) -
Park BuMahn,
Mun Soungyun,
Yun Jaesook
Publication year - 2006
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200606149
Subject(s) - enantioselective synthesis , hydrosilylation , chemistry , silane , catalysis , diamine , silanes , combinatorial chemistry , organic chemistry , metal , zinc
The highly enantioselective reduction of imines is achieved by employing chiral Zn/diamine catalysts. This new catalytic protocol offers attractive features such as use of a non‐precious metal and an inexpensive silane, easy modification of chiral diamine ligands and provides ready access to chiral amines in good yields and with excellent enantioselectivities.