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Iron‐Salen Complexes as Efficient Catalysts in Ring Expansion Reactions of Epoxyalkenes
Author(s) -
Hilt Gerhard,
Walter Christian,
Bolze Patrick
Publication year - 2006
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200606107
Subject(s) - chemistry , intramolecular force , ring (chemistry) , phosphine , ligand (biochemistry) , catalysis , metal salen complexes , polymer chemistry , medicinal chemistry , combinatorial chemistry , organic chemistry , receptor , biochemistry
The optimisation of the iron‐catalysed ring expansion reaction of epoxyalkenes was considerably improved when the original phosphine ligand system [FeCl 2 (dppe)] was altered to include nitrogen‐containing ligand systems. Especially, the very potent class of salen ligands gave the best results in inter‐ and intramolecular ring expansion reactions. With a preformed iron( II )‐salen complex the yields and diastereoselectivities were greatly enhanced and the scope of the reaction could also be enlarged.