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An Effective Bismuth‐Catalyzed Benzylation of Arenes and Heteroarenes
Author(s) -
Rueping Magnus,
Nachtsheim Boris J.,
Ieawsuwan Winai
Publication year - 2006
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200606068
Subject(s) - chemistry , intramolecular force , catalysis , bismuth , combinatorial chemistry , scope (computer science) , simplicity , environmentally friendly , organic chemistry , reaction conditions , computer science , ecology , philosophy , epistemology , biology , programming language
A highly efficient Bi(OTf) 3 ‐catalyzed benzylation of arenes and heteroarenes has been developed. The mild reaction conditions, high yields, operational simplicity and practicability, broad scope, and remarkably low catalyst loading render this environment friendly process an attractiv approach to diarylmethane derivatives. The extension to an intramolecular variant of this procedure provides a valuable route to substituted fluorenes.