Premium
Improved Enantioselectivity of Immobilized Chiral Bisoxazolines by Partial Precapping of the Siliceous Mesocellular Foam Support with Trimethylsilyl Groups
Author(s) -
Lee Su Seong,
Hadinoto Sukandar,
Ying Jackie Y.
Publication year - 2006
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200606027
Subject(s) - chemistry , cyclopropanation , trimethylsilyl , catalysis , enantioselective synthesis , combinatorial chemistry , polymer chemistry , organic chemistry , chemical engineering , engineering
Siliceous mesocellular foams (MCF) were partially surface‐modified with trimethylsilyl (TMS) groups prior to the immobilization of chiral tert ‐butylbisoxazolines. The resulting MCF‐supported bisoxazoline‐Cu(I) catalyst showed superior enantioselectivity (up to 95 % ee ) in asymmetric cyclopropanation, compared to that supported on MCF without TMS precapping. This heterogenized catalyst also exhibited excellent recyclability.