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Palladium‐Catalyzed Stereoselective Synthesis of (E) ‐Stilbenes via Organozinc Reagents and Carbonyl Compounds
Author(s) -
Wang JinXian,
Wang Kehu,
Zhao Lianbiao,
Li Hongxia,
Fu Ying,
Hu Yulai
Publication year - 2006
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200606016
Subject(s) - chemistry , stereoselectivity , reagent , catalysis , halide , palladium , organic chemistry , reaction conditions , medicinal chemistry , combinatorial chemistry
In the presence of a catalytic amount of PdCl 2 (PPh 3 ) 2 and a silylating agent, organozinc halides reacted with carbonyl compounds to give the corresponding ( E )‐stilbenes in good to excellent yields under mild conditions. The reaction mechanism is briefly discussed.