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Friedländer Synthesis of Quinolines Using a Lewis Acid‐Surfactant‐Combined Catalyst in Water
Author(s) -
Zhang Liang,
Wu Jie
Publication year - 2007
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200600527
Subject(s) - chemistry , scandium , catalysis , lewis acids and bases , annulation , lewis acid catalysis , pulmonary surfactant , organic chemistry , tris , biochemistry
In water, Friedländer annulation using Lewis acid‐surfactant‐combined catalyst provides a mild and efficient route for the synthesis of quinolines. Employing a catalytic amount of scandium tris(dodecyl sulfate) [Sc(O 3 SOC 12 H 25 ) 3 ], various polysubstituted and polycyclic quinolines were obtained in exellent yields.