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Chiral Ionic Phosphites and Diamidophosphites: A Novel Group of Efficient Ligands for Asymmetric Catalysis
Author(s) -
Gavrilov Konstantin N.,
Lyubimov Sergey E.,
Bondarev Oleg G.,
Maksimova Marina G.,
Zheglov Sergey V.,
Petrovskii Pavel V.,
Davankov Vadim A.,
Reetz Manfred T.
Publication year - 2007
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200600372
Subject(s) - chemistry , rhodium , cationic polymerization , catalysis , denticity , asymmetric hydrogenation , enantioselective synthesis , allylic rearrangement , palladium , transition metal , medicinal chemistry , organic chemistry , combinatorial chemistry , metal , polymer chemistry
Seven members of a new class of chiral P‐monodentate cationic phosphites and diamidophosphites have been synthesized for the first time and tested as ligands in asymmetric transition metal catalysis. Up to 96 % ee was achieved in the rhodium‐catalyzed asymmetric hydrogenation of functionalized olefins and up to 99 % ee in the palladium‐catalyzed allylic allylation. Applications of the immobilized cationic rhodium complex to asymmetric catalytic synthesis have also been demonstrated.