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A New Metal‐Free Access to Vitamin K3
Author(s) -
Bohle Anne,
Schubert Anett,
Sun Yu,
Thiel Werner R.
Publication year - 2006
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200505491
Subject(s) - chemistry , regioselectivity , hydrogen peroxide , catalysis , yield (engineering) , metal , transition metal , organic chemistry , metallurgy , materials science
2‐Methylnaphthalene is oxidized in about 80 % yield with 7–9/1 regioselectivity to 2‐methyl‐1,4‐naphthoquinone by hydrogen peroxide with a strong mineral acid as the catalyst. No (transition) metal catalyst is required for this transformation.