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Cobalt‐Catalysed Addition of Allylidene Dipivalate to Aldehydes. A Formal Homoaldol Condensation
Author(s) -
Lombardo Marco,
Licciulli Sebastiano,
Pasi Filippo,
Angelici Gaetano,
Trombini Claudio
Publication year - 2005
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200505212
Subject(s) - chemistry , aldehyde , cobalt , acetonitrile , condensation , catalysis , redox , condensation reaction , organic chemistry , physics , thermodynamics
A Co(I)‐catalysed condensation of allylidene dipivalate with aldehydes to give ( Z )‐4‐hydroxybut‐1‐enyl pivalates in 62 to 87% isolated yields, is reported. Reactions are run in acetonitrile at 0 or 25 °C depending on the nature of the aldehyde, and exploiting the Co(II)/Zn(0) redox couple for the preparation of the catalytic Co(I) species.