Premium
Ruthenium(III) Chloride‐Catalyzed Thioacetalization of Carbonyl Compounds: Scope, Selectivity, and Limitations
Author(s) -
De Surya Kanta
Publication year - 2005
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200404323
Subject(s) - chemistry , ruthenium , chemoselectivity , acetonitrile , catalysis , chloride , selectivity , combinatorial chemistry , organic chemistry
A variety of carbonyl compounds can be easily and rapidly converted to the corresponding cyclic and acylic dithioacetals in the presence of a catalytic amount of ruthenium chloride in acetonitrile at room temperature. Some of the major advantages of this protocol are high chemoselectivity, operational simplicity, very short reaction times, high yields, and also compatibility with other protecting groups.