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Base‐Catalyzed Condensation of 2‐Hydroxybenzaldehydes with α,β‐Unsaturated Aldehydes – Scope and Limitations
Author(s) -
Lesch Bernhard,
Toräng Jakob,
Vanderheiden Sylvia,
Bräse Stefan
Publication year - 2005
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200404239
Subject(s) - chemistry , aldol condensation , scope (computer science) , catalysis , base (topology) , conjugated system , condensation , combinatorial chemistry , aldol reaction , organic chemistry , mathematical analysis , polymer , physics , mathematics , computer science , thermodynamics , programming language
The base‐catalyzed condensation of α,β‐unsaturated carbonyl compounds with 2‐hydroxybenzaldehydes yielding tetrahydroxanthones and dihydrobenzopyrans has been investigated. A novel access to highly functionalized dihydrobenzopyrans via a mild generation of the dienol of senecialdehyde and subsequent conjugated aldol reaction has been reported.

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