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A Practical and Chemoselective Reduction of Nitroarenes to Anilines Using Activated Iron
Author(s) -
Liu Yugang,
Lu Yansong,
Prashad Mahavir,
Repič Oljan,
Blacklock Thomas J.
Publication year - 2005
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200404236
Subject(s) - chemistry , nitrile , ketone , alkyne , enone , organic chemistry , reduction (mathematics) , methyl isobutyl ketone , halide , combinatorial chemistry , catalysis , mathematics , geometry
Reduction of nitroarenes to anilines using activated iron generated by Fe/HCl or Zn/FeSO 4 is described. A variety of functional groups such as alkyne, ketone, enone, nitrile, lactone, and aromatic halide are well tolerated under these conditions.