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On the Stereochemical Course of Self‐Replication in Secondary Cycle Sharpless Aminohydroxylation
Author(s) -
Muñiz Kilian
Publication year - 2005
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200404209
Subject(s) - chemistry , olefin fiber , replication (statistics) , enantiomer , computational chemistry , stereochemistry , organic chemistry , catalysis , mathematics , statistics
An investigation on a potential asymmetric self‐replication process within the secondary cycle of Sharpless asymmetric aminohydroxylation is discussed. The reaction of two model olefins is investigated within this process and two different models for an asymmetric process are discussed. Analysis of the results on the basis of these models and a mathematical description for development of the enantiomeric excesses as a function of olefin conversion lead to the conclusion that for such processes there is no possibility for any inhibitory effect and that asymmetric self‐replication in secondary cycle aminohydroxylation reactions is not a feasible process.