A Domino Copper‐Catalyzed CN and CO Cross‐Coupling for the Conversion of Primary Amides into Benzoxazoles | Zendy

Altenhoff Gereon | Zendy; Glorius Frank | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

A Domino Copper‐Catalyzed CN and CO Cross‐Coupling for the Conversion of Primary Amides into Benzoxazoles

Author(s) -

Altenhoff Gereon,

Glorius Frank

Publication year - 2004

Publication title -

advanced synthesis and catalysis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.541

H-Index - 155

eISSN - 1615-4169

pISSN - 1615-4150

DOI - 10.1002/adsc.200404182

Subject(s) - chemistry , domino , catalysis , regioselectivity , yield (engineering) , copper , primary (astronomy) , cascade reaction , combinatorial chemistry , medicinal chemistry , coupling reaction , coupling (piping) , organic chemistry , metallurgy , materials science , physics , astronomy

Benzoxazoles can be efficiently prepared in a single step and in good yield from primary amides and o ‐dihalobenzenes using Cu catalysis. Starting from substituted o ‐bromochlorobenzenes this unusual domino reaction allows the regioselective formation of benzoxazoles.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research