Asymmetric Hydrogenation of Quinolines Catalyzed by Iridium with Chiral Ferrocenyloxazoline Derived N,P Ligands
Author(s) -
Lu ShengMei,
Han XiuWen,
Zhou YongGui
Publication year - 2004
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200404017
Subject(s) - iridium , chemistry , asymmetric hydrogenation , catalysis , chirality (physics) , enantioselective synthesis , planar chirality , noyori asymmetric hydrogenation , combinatorial chemistry , medicinal chemistry , stereochemistry , organic chemistry , chiral symmetry , physics , quark , nambu–jona lasinio model , quantum mechanics
Abstract Chiral ferrocenyloxazoline derived N,P ligands are used in the iridium‐catalyzed asymmetric hydrogenation of quinolines, and up to 92% ee was obtained. The role of the planar chirality is also studied.