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Catalytic Carbon‐Fluorine Bond Activation with Monocoordinated Nickel‐Carbene Complexes: Reduction of Fluoroarenes
Author(s) -
Kuhl Sébastien,
Schneider Raphaël,
Fort Yves
Publication year - 2003
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200390036
Subject(s) - chemistry , carbene , imes , catalysis , nickel , reactivity (psychology) , medicinal chemistry , aryl , fluorine , photochemistry , alkoxide , organic chemistry , alkyl , medicine , alternative medicine , pathology
Monocoordinate nickel/ N ‐heterocyclic carbene complexes reveal unexpected reactivity towards aryl fluorides. Defluorination reactions were efficiently performed with a β‐hydrogen‐containing alkoxide (3 equiv.) in the presence of 3 mol % of [1:1] Ni(0)/IMes⋅HCl catalyst (IMes=1,3‐dimesitylimidazol‐2‐ylidene).