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Iridium‐Catalyzed Enantioselective Hydrogenation of Imines with Xylose Diphosphite and Diphosphinite Ligands
Author(s) -
Guiu Ester,
Muñoz Bianca,
Castillón Sergio,
Claver Carmen
Publication year - 2003
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200390005
Subject(s) - iridium , chemistry , enantioselective synthesis , catalysis , xylose , asymmetric hydrogenation , ligand (biochemistry) , chirality (physics) , organic chemistry , combinatorial chemistry , biochemistry , fermentation , receptor , chiral symmetry breaking , physics , quantum mechanics , quark , nambu–jona lasinio model
Iridium complexes incorporating xylose diphosphinite 1 and diphosphite 2, 3 ligands as source of chirality are active catalysts for the hydrogenation of imines providing moderate ee. The enantioselectivity depends on the fine tuning of the structural parameters of the ligand and on the effect of additives.