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N ‐Methylprolinol Catalysed Asymmetric Baylis−Hillman Reaction
Author(s) -
Radha Krishna Palakodety,
Kannan V.,
Narasimha Reddy P. V.
Publication year - 2004
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200303217
Subject(s) - chemistry , baylis–hillman reaction , adduct , catalysis , base (topology) , medicinal chemistry , organocatalysis , organic chemistry , reaction conditions , enantioselective synthesis , mathematical analysis , mathematics
N ‐methylprolinol is used as a chiral base catalyst for the Baylis–Hillman reaction to obtain the adducts in good yields with moderate to good enantioselectivities in 1,4‐dioxane:water (1 : 1, v/v) under ambient conditions.
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