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A Simple and Highly Selective Biomimetic Oxidation of Alcohols and Epoxides with N ‐Bromosuccinimide in the Presence of β‐Cyclodextrin in Water
Author(s) -
Krishnaveni N. Srilakshmi,
Surendra K.,
Rama Rao K.
Publication year - 2004
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200303164
Subject(s) - chemistry , n bromosuccinimide , cyclodextrin , alcohol oxidation , solvent , catalysis , organic chemistry , combinatorial chemistry , halogenation
A simple, mild and highly efficient biomimetic oxidation of various alcohols and epoxides with N ‐bromosuccinimide (NBS) catalyzed by β‐cyclodextrin in water has been developed. A series of alcohols and epoxides were oxidized selectively at room temperature in excellent yields. This method is a direct one‐pot synthesis under mild conditions using water as solvent and has many advantages over the existing methodologies.