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Biophotonics: Dendrimeric DNA Nanostructures as Scaffolds for Efficient Bidirectional BRET–FRET Cascades (Advanced Optical Materials 14/2017)
Author(s) -
Brown Carl W.,
Samanta Anirban,
Díaz Sebastián A.,
BuckhoutWhite Susan,
Walper Scott A.,
Goldman Ellen R.,
Medintz Igor L.
Publication year - 2017
Publication title -
advanced optical materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 91
ISSN - 2195-1071
DOI - 10.1002/adom.201770074
Subject(s) - förster resonance energy transfer , biophotonics , nanotechnology , biosensor , materials science , dendrimer , energy transfer , microscale chemistry , dna , dna origami , nanostructure , dna nanotechnology , biophysics , fluorescence , optoelectronics , photonics , chemistry , biology , biochemistry , physics , optics , engineering physics , mathematics education , mathematics , polymer chemistry
A dendrimeric DNA structure, explored by Igor L. Medintz and co‐workers in article number 1700181 , highlights how a bioluminescent enzyme can chemically initiate and drive an energy transfer cascade through multiple sequential dyes appended on the DNA. The schematic (by Ella Maru Studios) highlights a fork in the dendrimer along with 2 luciferase enzymes and sets of dyes feeding into a common final acceptor. Such self‐assembled structures can function in a stand‐alone mode as they both create and harvest their own light energy. This suggests them as potential platforms for stand‐alone biosensing.