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Live Cell Imaging: Extraordinary Transmission‐based Plasmonic Nanoarrays for Axially Super‐Resolved Cell Imaging (Advanced Optical Materials 1/2014)
Author(s) -
Choi Jongryul,
Kim Kyujung,
Oh Youngjin,
Kim Ah Leum,
Kim Sook Young,
Shin JeonSoo,
Kim Donghyun
Publication year - 2014
Publication title -
advanced optical materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 91
ISSN - 2195-1071
DOI - 10.1002/adom.201470001
Subject(s) - materials science , axial symmetry , plasmon , optics , fluorescence lifetime imaging microscopy , transmission (telecommunications) , cholera toxin , fluorescence , optical imaging , optoelectronics , physics , electrical engineering , microbiology and biotechnology , quantum mechanics , biology , engineering
Extraordinary transmission‐based axial imaging (EOT‐AIM) is developed for cell microscopy by J.‐S. Shin, D. Kim, and co‐workers, in which localization by nanoaperture arrays performs near‐field sampling of target fluorescence up to a preset axial distance. EOT‐AIM achieves an axial super‐resolution as small as 20 nm for a depth range of 500 nm. On page 48, the measurement of intracellular cholera toxin subunit B conjugated with FITC successfully confirms that both the resolution and the axial imaging range are improved significantly as compared to conventional methods.