Premium
Label‐Free Biosensor Based on an All‐Polymer DFB Laser
Author(s) -
Heydari Esmaeil,
Buller Jens,
Wischerhoff Erik,
Laschewsky André,
Döring Sebastian,
Stumpe Joachim
Publication year - 2014
Publication title -
advanced optical materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 91
ISSN - 2195-1071
DOI - 10.1002/adom.201300454
Subject(s) - biosensor , materials science , analyte , laser , polymer , resonator , nanotechnology , optoelectronics , computer science , optics , chemistry , physics , composite material
A monolithic active optical resonator biosensor is fabricated for label‐free sensing. The all‐polymer sensor consists of a polymer distributed feedback (DFB) laser and a hydrogel recognition layer. Specific binding of analyte modulates the effective refractive index, shifting the laser emission wavelength. Real time detection of avidin–biotin interactions is demonstrated as a model for the new label‐free biosensing principle.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom