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Label‐Free Biosensor Based on an All‐Polymer DFB Laser
Author(s) -
Heydari Esmaeil,
Buller Jens,
Wischerhoff Erik,
Laschewsky André,
Döring Sebastian,
Stumpe Joachim
Publication year - 2014
Publication title -
advanced optical materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 91
ISSN - 2195-1071
DOI - 10.1002/adom.201300454
Subject(s) - biosensor , materials science , analyte , laser , polymer , resonator , nanotechnology , optoelectronics , computer science , optics , chemistry , physics , composite material
A monolithic active optical resonator biosensor is fabricated for label‐free sensing. The all‐polymer sensor consists of a polymer distributed feedback (DFB) laser and a hydrogel recognition layer. Specific binding of analyte modulates the effective refractive index, shifting the laser emission wavelength. Real time detection of avidin–biotin interactions is demonstrated as a model for the new label‐free biosensing principle.