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Stem Cell Nests: Design Artificial Stem Cell Nests for Stem Cell Niche in a Microfluidic Petri Dish Programmed by a Cell Phone (Adv. Mater. Technol. 6/2021)
Author(s) -
Peng Xing Yue Larry,
Guo Yaxin,
Peng Linghan,
Liu Juan
Publication year - 2021
Publication title -
advanced materials technologies
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.184
H-Index - 42
ISSN - 2365-709X
DOI - 10.1002/admt.202170035
Subject(s) - petri dish , stem cell , stem cell niche , microfluidics , embryonic stem cell , cell , microbiology and biotechnology , niche , biology , computer science , materials science , nanotechnology , progenitor cell , genetics , ecology , gene
In article number 2100045, Xing Yue (Larry) Peng and co‐workers develop microfluidic petri dishes that precisely control four ultra‐slow micro circulations (<40 μm s −1 ) in a 10 mm artificial stem cell niche. The microfluidic petri dishes need only a 1.8 mm magnet bead, an earplug‐size actuator, and the ability to edit an MP3 song playlist to program the niche of an artificial cell nest. The single clone area of embryonic stem cells increases 15 times in a 4‐day automatic culture with only five drops of culture medium supplement every two days.