Premium
Self‐Assembled Nanoparticles as Cancer Therapeutic Agents
Author(s) -
Ge Wei,
Wang Lei,
Zhang Jiayao,
Ou Changjin,
Si Weili,
Wang Wenjun,
Zhang Qingming,
Dong Xiaochen
Publication year - 2021
Publication title -
advanced materials interfaces
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.671
H-Index - 65
ISSN - 2196-7350
DOI - 10.1002/admi.202001602
Subject(s) - nanotechnology , materials science , biocompatibility , cancer therapy , nanoparticle , supramolecular chemistry , non covalent interactions , cancer , medicine , chemistry , organic chemistry , molecule , hydrogen bond , metallurgy
Most therapeutic agents for cancer are currently suffering from the shortcomings of poor solubility, severe side effects, and multidrug resistance. Supramolecular self‐assembly (SSA) in nanomedicines is a promising way to overcome these obstacles due to the distinguished properties of noncovalent self‐assembly such as functional diversity, easy stimulus‐response, high biocompatibility, and biodegradability. Moreover, it is more potential to transform them from lab to clinic. In this review, based on lots of state‐of‐the‐art studies, a summary is presented about the recent advances in SSA for cancer treatment, with the introduction of noncovalent driving forces, classifications, design, and applications of multifunctional self‐assembled nanoparticles (SANPs). Finally, the prospects of SANPs on both developing drugs and clinical transformation are discussed.