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Optically and Structurally Stabilized Plasmo‐Bio Interlinking Networks
Author(s) -
Lin WeiKuan,
Cui Guangjie,
Burns Zachary,
Zhao Xintao,
Liu Yunbo,
Zhang Zhijia,
Wang Yi,
Ye Xingchen,
Park Younggeun,
Lee Somin Eunice
Publication year - 2021
Publication title -
advanced materials interfaces
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.671
H-Index - 65
ISSN - 2196-7350
DOI - 10.1002/admi.202001370
Subject(s) - materials science , nanorod , nanotechnology , biocompatible material , visualization , plasmon , photobleaching , computer science , optoelectronics , optics , fluorescence , artificial intelligence , medicine , physics , biomedical engineering
Abstract Visualization of dynamic interlinking networks which respond and adapt to the constantly changing environment would be highly beneficial in developing new composite materials and active/responsive materials. Here, optically and structurally stabilized plasmo‐bio interlinking networks (PBINs) free from photobleaching for high resolution, long term visualization are reported. Necessary for structural and optical stability, a new stability algorithm to comprehensively quantify stability and detect minute instability undetectable by traditional methods is introduced. Biocompatible plasmonic gold nanorods (Bio‐AuNRs) are synthesized for high resolution, long term imaging by utilizing bromide‐free alternatives to achieve CTA+ free. Systematic physical, chemical, and biological characterizations reveal the structural and optical stability of Bio‐AuNRs required for constructing PBIN. Lastly, with actin as a model of interlinking networks of the cytoskeleton, optically and structurally stable PBIN (100% CTA+ free, 97% crosslinking rate) in applications as active/responsive materials, are demonstrated.