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Osseointegration: Antibacterial Mesoporous Titania Films with Embedded Gentamicin and Surface Modified with Bone Morphogenetic Protein 2 to Promote Osseointegration in Bone Implants (Adv. Mater. Interfaces 9/2019)
Author(s) -
Escobar Ane,
Muzzio Nicolás,
Coy Emerson,
Liu Hui,
Bindini Elisa,
Andreozzi Patrizia,
Wang Guocheng,
Angelomé Paula,
Delcea Mihaela,
Grzelczak Marek,
Moya Sergio E.
Publication year - 2019
Publication title -
advanced materials interfaces
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.671
H-Index - 65
ISSN - 2196-7350
DOI - 10.1002/admi.201970057
Subject(s) - osseointegration , materials science , mesoporous material , surface modification , bone morphogenetic protein 2 , biomedical engineering , nanotechnology , gentamicin , osteoblast , chemical engineering , implant , chemistry , medicine , biochemistry , in vitro , surgery , catalysis , antibiotics , engineering
Mesoporous Titania Films (MTFs) are synthesized through the sol‐gel technique for gentamicin loading and delivery, and the functionalization of the MTFs surface with human recombinant bone morphogenetic protein 2. This doubly functionalized MTFs have been shown to be effective against S. aureus colonization and the presence of hrBMP‐2 enhances MC3T3‐E1 pre‐osteoblast cell attachment, proliferation and differentiation. More details can be found in article number 1801648 by Ane Escobar, Sergio E. Moya, and co‐workers.