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Cell Motility: Surface‐Grafted Nanogel Arrays Direct Cell Adhesion and Motility (Adv. Mater. Interfaces 20/2016)
Author(s) -
Sechi Antonio,
Freitas Joana M. G.,
Wünnemann Patrick,
Töpel Alexander,
Paschoalin Rafaella T.,
Ullmann Sabrina,
Schröder Ricarda,
Aydin Gülcan,
Rütten Stephan,
Böker Alexander,
Zenke Martin,
Pich Andrij
Publication year - 2016
Publication title -
advanced materials interfaces
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.671
H-Index - 65
ISSN - 2196-7350
DOI - 10.1002/admi.201670097
Subject(s) - motility , nanogel , materials science , adhesion , cell adhesion , biophysics , nanotechnology , cell , fabrication , composite material , microbiology and biotechnology , drug delivery , chemistry , biology , biochemistry , medicine , alternative medicine , pathology
Antonio Sechi and co‐workers describe the fabrication of highly functional and stimuli‐responsive nanogel arrays grafted onto glass surfaces by a printing process using wrinkled PDMS templates in article 1600455. These nanogels influence size and dynamics of focal adhesions as well as cell motility forcing cells to move along highly directional trajectories. The modulation of nanogel topographical and mechanical properties by temperature or spacing serves as an effective tool for the regulation of cell motility.