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Protein Nanotubes: Purification and Characterization of Protein Nanotubes Assembled from a Single Bacterial Microcompartment Shell Subunit (Adv. Mater. Interfaces 1/2016)
Author(s) -
Noël Christopher R.,
Cai Fei,
Kerfeld Cheryl A.
Publication year - 2016
Publication title -
advanced materials interfaces
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.671
H-Index - 65
ISSN - 2196-7350
DOI - 10.1002/admi.201670002
Subject(s) - materials science , nanotechnology , biomaterial , protein subunit , escherichia coli , shell (structure) , in vivo , nanotube , in vitro , biophysics , carbon nanotube , chemistry , biology , biochemistry , microbiology and biotechnology , composite material , gene
In article number 1500295, C. A. Kerfeld and co‐workers report on self‐assembled protein nanotubes composed of a hexameric bacterial microcompartment (BMC) shell protein, which can be produced in and purified from Escherichia coli. Disassembly and re‐assembly of the nanotubes can also be achieved in vitro. BMC‐based nanotubes offer a new biomaterial and spatial architecture that may be genetically or chemically modified and used as a molecular scaffold in vivo or in vitro.