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Dual Responsive Surfaces Based on Host–Guest Interaction for Dynamic Mediation of Cell–Substrate Interaction and Cell Migration
Author(s) -
Ren Tanchen,
Ni Yelin,
Du Wang,
Yu Shan,
Mao Zhengwei,
Gao Changyou
Publication year - 2017
Publication title -
advanced materials interfaces
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.671
H-Index - 65
ISSN - 2196-7350
DOI - 10.1002/admi.201500865
Subject(s) - azobenzene , substrate (aquarium) , dual (grammatical number) , materials science , mediation , on demand , nanotechnology , host (biology) , cell , computer science , polymer , biophysics , chemistry , multimedia , biochemistry , biology , genetics , art , ecology , literature , political science , law , composite material
A dual responsive surface is constructed on hydrophilic polymer brushes to modulate cell migration ability on demand. The responsibility is based on the dynamic host–guest interaction between β‐CD and azobenzene. Both competitive guest molecules and UV radiation are able to release azobenzene‐REDV from the substrate, weakening the cell–substrate interaction and modulating the cell migration rate.