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Enzyme‐Modified Hydrogel Coatings with Self‐Cleaning Abilities for Low Fouling PDMS Devices
Author(s) -
Zhang Hongbin,
Jackson John K.,
Bian Chao,
Burt Helen M.,
Chiao Mu
Publication year - 2015
Publication title -
advanced materials interfaces
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.671
H-Index - 65
ISSN - 2196-7350
DOI - 10.1002/admi.201500154
Subject(s) - polydimethylsiloxane , materials science , methacrylic acid , fouling , ethylene glycol , nanotechnology , polymer , membrane , chemical engineering , chemistry , composite material , polymerization , engineering , biochemistry
Enzyme‐containing hydrogel coatings with abilities to automatically degrade proteins are developed by covalently binding proteases onto poly(ethylene glycol)/methacrylic acid hydrogel surfaces. Such active coatings can be easily applied to hydrophobic polydimethylsiloxane (PDMS) surfaces to impart long‐term hydrophilicity and self‐cleaning ability, providing an effective and environmentally friendly way to resist protein fouling in the biologically related application of PDMS‐based devices.