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Detection of Single Nanoparticles and Lentiviruses Using Microcavity Resonance Broadening
Author(s) -
Shao Linbo,
Jiang XueFeng,
Yu XiaoChong,
Li BeiBei,
Clements William R.,
Vollmer Frank,
Wang Wei,
Xiao YunFeng,
Gong Qihuang
Publication year - 2013
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma201302572
A new label‐free sensing mechanism is demonstrated experimentally by monitoring the whispering‐gallery mode broadening in microcavities. It is immune to both noise from the probe laser and environmental disturbances, and is able to remove the strict requirement for ultra‐high‐Q mode cavities for sensitive nanoparticle detection. This ability to sense nanoscale objects and biological analytes is particularly crucial for wide applications.