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Antibacterial Action: Antibacterial Action of Nanoparticles by Lethal Stretching of Bacterial Cell Membranes (Adv. Mater. 52/2020)
Author(s) -
Linklater Denver P.,
Baulin Vladimir A.,
Le Guével Xavier,
Fleury JeanBaptiste,
Hanssen Eric,
Nguyen The Hong Phong,
Juodkazis Saulius,
Bryant Gary,
Crawford Russell J.,
Stoodley Paul,
Ivanova Elena P.
Publication year - 2020
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.202070389
Subject(s) - antibacterial activity , membrane , bacterial cell structure , materials science , nanotechnology , nanoparticle , bacteria , action (physics) , nanomaterials , antibiotics , cell membrane , colloidal gold , biophysics , microbiology and biotechnology , chemistry , biology , biochemistry , physics , genetics , quantum mechanics
The antibacterial action of large (>10 nm) spherical gold nanoparticles is demonstrated by Elena P. Ivanova and co‐workers in article number 2005679 to be attributed to the combined stretching and rupture of the bacterial cell membrane. The newly discovered mechanical modes of antibacterial action pose varied implications for the use and application of nanomaterials. The mechanical killing of bacteria in liquids by surface‐active nanom aterials provides another platform from which to combat the global health crisis of antibiotic resistance.