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Nano‐Ligands: Independent Tuning of Nano‐Ligand Frequency and Sequences Regulates the Adhesion and Differentiation of Stem Cells (Adv. Mater. 40/2020)
Author(s) -
Min Sunhong,
Jeon Yoo Sang,
Jung Hee Joon,
Khatua Chandra,
Li Na,
Bae Gunhyu,
Choi Hyojun,
Hong Hyunsik,
Shin Jeong Eun,
Ko Min Jun,
Ko Han Seok,
Jun Indong,
Fu Hong En,
Kim Seung Hyun,
Thangam Ramar,
Song JaeJun,
Dravid Vinayak P.,
Kim Young Keun,
Kang Heemin
Publication year - 2020
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.202070299
Subject(s) - materials science , nano , stem cell , adhesion , cell adhesion , nanotechnology , ligand (biochemistry) , mechanotransduction , microbiology and biotechnology , biophysics , biology , receptor , biochemistry , composite material
In article number 2004300, Young Keun Kim, Heemin Kang, and co‐workers report a magnetic nano‐barcoding system that enables unique tunability of ligand frequency and nano‐sequences to effectively regulate stem cell adhesion with no systemic toxicity in vivo. Low‐frequency and terminally sequenced nano‐ligands facilitate focal adhesion, mechanotransduction, and differentiation of stem cells.