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Helical Peptide Nanofibers: Controlled Lengthwise Assembly of Helical Peptide Nanofibers to Modulate CD8 + T‐Cell Responses (Adv. Mater. 39/2020)
Author(s) -
Fries Chelsea N.,
Wu Yaoying,
Kelly Sean H.,
Wolf Michelle,
Votaw Nicole L.,
Zauscher Stefan,
Collier Joel H.
Publication year - 2020
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/adma.202070295
Subject(s) - nanofiber , materials science , peptide , nanotechnology , character (mathematics) , biophysics , polymer science , biochemistry , biology , geometry , mathematics
In nanofibers composed of self‐assembling helical peptides, “capping” peptides can limit fiber growth and influence the character of immune responses raised by the materials. In article number 2003310, Joel H. Collier and co‐workers design short peptides such that they self‐assemble into immunologically active helical nanofibers. The lengths of these fibers, tailorable by the incorporation of structure‐modifying peptides within the assemblies, influence the character of the immune responses they elicit. Image Credit: Chelsea Fries and Joel Collier.